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L-Histidine monohydrochloride monohydrat

CAS No. 5934-29-2

L-Histidine monohydrochloride monohydrat ( —— )

Catalog No. M19639 CAS No. 5934-29-2

Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids i.e. the building blocks of proteins.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    L-Histidine monohydrochloride monohydrat
  • Note
    Research use only not for human use.
  • Brief Description
    Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids i.e. the building blocks of proteins.
  • Description
    Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids i.e. the building blocks of proteins. It is classified as a charged polar because of the hydrophilic nature of the imidazole side chain. L-Histidine is a positively charged (pKa 6.5) aromatic amino acid. Histidine residues are often found in enzyme active sites where the chemistry of the imidazole ring of histidine makes it a nucleophile and a good acid/base catalyzer. Histidine is special in that its biosynthesis is inherently linked to the pathways of nucleotide formation. In the first step of histidine synthesis PRPP (5-phosphoribosyl-alpha-pyrophosphate) condenses with ATP to form a purine N1-5'-phosphoribosyl ATP in a reaction that is driven by the subsequent hydrolysis of the pyrophosphate that condenses out. Glutamine plays a role as an amino group donor resulting in the formation of 5-aminoamidazole-4-carboximide ribonucleotide (ACAIR) which is an intermediate in purine biosynthesis. Hisitidne is catabolized by the enzyme histidine ammonia-lyase which converts histidine into ammonia and urocanic acid.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Others
  • Indication
    accessory substance

Chemical Information

  • CAS Number
    5934-29-2
  • Formula Weight
    209.63
  • Molecular Formula
    C6H12ClN3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    O.Cl.N[C@@H](Cc1cnc[nH]1)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.De?Sousa G.P. Freire P.T.C. Filho J.M. et al. Braz J Phys (2013) 43: 137. https://doi.org/10.1007/s13538-013-0132-3
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